OpenEvidence

Evidence-based clinical answers for physicians, in real time.

OpenEvidence is an AI platform built for physicians and clinicians that answers clinical questions by searching and synthesizing current medical literature, guidelines, and evidence sources in real time. Rather than relying on a model’s training data alone, OpenEvidence retrieves and reasons over live medical evidence to produce answers that are grounded, cited, and up to date — addressing the core trust issue that general-purpose AI assistants face in clinical settings where outdated or hallucinated information has patient safety implications. The platform is free for individual clinicians and has achieved significant adoption, with over 500,000 clinicians reported as users. It differentiates through its focus on clinical accuracy, evidence grounding, and a medical-specific AI model, rather than adapting a general-purpose LLM for healthcare questions.

Compliance

HIPAA SOC 2

Visit OpenEvidence

Key Features

Real-time medical literature synthesis: Retrieves and synthesizes evidence from current medical literature and clinical guidelines to answer questions, rather than relying solely on static training data.
Cited, evidence-grounded answers: Every answer is linked back to the source literature, allowing clinicians to verify the basis of a recommendation and maintain the rigor that clinical decision-making requires.
Proprietary medical AI model: Uses an AI model developed specifically for medical reasoning and clinical question answering, trained and evaluated against clinical accuracy standards rather than general benchmarks.
Broad clinical question coverage: Handles a wide range of clinical queries — drug interactions, diagnostic criteria, treatment protocols, dosing — that arise in day-to-day clinical practice.
Free access for clinicians: Available at no cost to individual physicians and clinicians, removing the financial barrier to adoption at the point of care.
Enterprise tier for health systems: Offers an enterprise version for health systems or organizations that want to deploy OpenEvidence at scale with additional integration, compliance, or administrative features.

Use Cases

For physicians answering clinical questions at the point of care: A physician seeing a patient with an unusual presentation uses OpenEvidence to quickly retrieve evidence-based guidance on diagnosis or treatment, getting a cited answer in seconds rather than manually searching PubMed or UpToDate.
For health systems providing clinicians with a trusted AI tool: A health system wants to give its clinical staff access to a reliable AI assistant for clinical questions without the risk of deploying a general-purpose LLM that may produce inaccurate medical information.

Pricing MODELS

Freemium

Pricing Summary

OpenEvidence is free for individual clinicians. Enterprise pricing for health systems and organizations is available on a custom quote basis. Pricing details for the enterprise tier are not publicly listed.